Scientist Biostatistics

Scientist Biostatistics

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The Scientist Biostatistics has sufficient experience working as a statistician in the pharmaceutical industry to independently perform and lead statistical work within a project, an indication within a more complex project or be recognized as a methodology expert. This individual is able to lead and direct Biometrics work either in house or partnering with CROs to ensure delivery to quality and time.

Responsibilities:

• For a project or indication in clinical or preclinical therapeutic areas
• Leading the delivery and oversight on a multiple studies/indication within a project, potentially as a Global Project Statistician for a standard drug project
• Contributing to statistical methodological advances

The accountabilities for supporting projects directly include:

• Lead the statistical thinking and contributions to the delivery of studies, development plans, regulatory strategy, health technology assessment and/or commercial activities
• Direct project work, including statistical staff and/or CRO partners, to ensure delivery to standards, quality and time
• Develop design options and provide high quality decision support to enable the business to make informed decisions about a study or project
• Quantify the benefit, risk, value and uncertainty of the emerging asset/product profile
• Investigate and apply novel statistical approaches, for relevant statistical issues and/or regulatory guidance and/or value demonstration, including modelling and simulation
• Mentor/coach and support the education and training of statistics staff

The accountabilities for supporting statistical methodological advances include:

• Ability to consult across project teams within area of expertise
• Application of expert skills to investigate, apply novel statistical approaches, for relevant statistical issues and/or regulatory guidance and/or value demonstration, including modelling and simulation
• Produce pragmatic solutions, often within a tight time scale where the emphasis will be to deliver first, then refine and develop solutions thereafter
• Contribute to/or lead the development of a process improvement and/or capability area within the department
• Establish and improve standards, apply innovative statistical approaches to improve effectiveness and efficiency
• Interact with external scientists and represent AstraZeneca Biometrics externally through publications and presentations on novel statistical approaches and standard methodology
• Mentor/coach and support the education and training of statistics staff in the technical arena

Essential:

• MSc/PhD in Statistics, Mathematics (containing a substantial statistical component), or recognized equivalent to stats MSc
• Strong knowledge of programming in R and/or SAS
• Knowledge of the technical and regulatory requirements related to the role
• Excellent communication skills and ability to build strong relationships
• Experienced PhD in Statistics or a relevant topic
• Experience of independent research
• Delivering innovative statistical solutions in an applied environment

Desirable:

• Project Management Skills
• Proficiency in SAS and R/Python languages
• Knowledge of Bayesian statistics from theory to computation is a plus
• Track record of research and methodological development in Statistics, supported by scientific publications in first class statistical journals.

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AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing [email protected].