Research Associate I - In Vitro Biology

Company Description

Zymeworks is a publicly listed (NASDAQ:ZYME) R&D and clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation, bispecific and multifunctional biotherapeutics, initially focused on the treatment of cancer. Zymeworks' suite of complementary therapeutic platforms and its fully-integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly-differentiated product candidates. We are a global company headquartered in Vancouver, BC, with operations in Bellevue, WA, Dublin, Ireland, Singapore and Redwood City, CA.

Why Work With Us

Nothing is more critical to our success than the quality of our team. The work we do is meaningful and impactful - we care about each other as well as the patients we serve. We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance.

This role will be located in Vancouver and is full-time onsite.

How You'll Contribute

Zymeworks is seeking a Research Associate I to join the In Vitro Biology group within the ADC Therapeutic Development department. The In Vitro Biology group is responsible for the in vitro functional characterization and advancement of Antibody Drug Conjugate (ADC) therapeutic candidates and platform technologies. The successful candidate will be part of a dynamic and motivated team responsible for supporting pipeline program advancement and contributing to core platform technology improvements and innovation. The candidate will be challenged to critically analyze results and contribute to the Zymeworks team effort to create clinically and commercially relevant therapeutics.

Zymeworks is seeking a highly-motivated professional who is looking to grow their career with our company. This position will report to Associate Scientist, In Vitro Biology, ADC Therapeutic Development and will be based in Vancouver, BC.

What You'll Do

• Performs in vitro experiments for the functional characterization of bioconjugates or ADCs for different pipeline programs, using various cell-based assays and techniques including flow cytometry, high throughput screening, live cell imaging, 3D tissue culture, and other methods as required, to support pipeline project advancement.
• Supports mammalian tissue culture activities in In Vitro Biology group, maintaining numerous immortalized tumour and normal cell lines in culture.
• Works with team to ensure cell lines are properly expanded, cryopreserved and databases updated as required.
• Contributes to experimental design and supports novel assay development by troubleshooting methods.
• Applies knowledge of scientific methodologies in conducting data analysis and interpretation. Prepares and disseminates data presentations for group meetings, communicating and summarizing experiment results.
• Adheres to Zymeworks standard procedures for generating, documenting, and archiving data, maintaining an accurate, up-to-date electronic laboratory notebook.
• May contribute to scientific papers.
• Conducts all activities in accordance with scientific standards, OS&H regulations and established Zymeworks’ policies and practices. Contributes to a safe and highly efficient laboratory environment.

What You'll Bring

• Requires a BSc in a scientific discipline (Molecular Biology, Cell Biology, Immunology, Microbiology, etc.) and a minimum of 0-1 years’ related experience.
• Experience with mammalian tissue culture, cell line expansion, and aseptic technique strongly recommended and considered an asset.
• Ability to manage multiple projects, prioritize work and experiments, and deliver on deadlines.
• Experience with characterization and analysis of biotherapeutics (antibodies, ADCs or other protein or immunoconjugates) is an asset.
• Experience with cell-based or biochemical assay development and in vitro cancer models is an asset.
• Good analytical and problem-solving capabilities.
• Adhere to the highest degree of professional standards and strict confidentiality on matters that require discretion.
• Good organizational and time management skills and the ability to work effectively in a fast paced, fast changing environment.
• Excellent interpersonal skills with the ability to work collaboratively as a member of a cross-functional team; ability to establish and maintain effective working relationships.
• Excellent communication skills, including technical writing and oral skills. Ability to present data effectively at group meetings.
• Knowledge of antibody or antibody drug conjugate structure/function considered an asset.
• Knowledge of GraphPad and FlowJo softwares considered an asset.
• Knowledge and proficiency in the following techniques: Flow cytometry, High-content analysis or fluorescence imaging, Mammalian tissue culture, and Immunological/co-culture assays considered an asset.

Total Rewards

We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth. We regularly benchmark our compensation against leading biotechnology companies in our geographies.

The base salary range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position in the location for which the job is posted and does not include bonus, equity, or benefits. Within the range, individual pay is determined by a variety of factors and the salary offered may vary depending on the successful candidate’s location and qualifications (including, but not limited to, job-related knowledge, education, training, skills, and experience).

Our total rewards package that includes:

• Industry leading vacation and paid time off
• Exceptional medical, dental and vision benefits by country
• Zymelife health and wellness benefits
• Matching RRSP / 401K / Pension program
• Employee Share Purchase Program
• Employee Equity Program
• Paid time off to volunteer in your community

This role is not eligible for relocation or immigration support.

All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin or disability.

NOTE TO AGENCIES: Zymeworks values our relationships with our recruiting partners. We only accept resumes from those partners who have been contracted with us. Zymeworks is not responsible for any fees related to resumes that are unsolicited or are received without contract.

The pay range for this role is:

51,750 - 79,350 CAD per year (CA)